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Cohera Gives Distribution Rights of its Surgical Sealant to Terumo in Japan

Published on 2017-09-25. Author : SpecialChem

Cohera Medical has announced that it has signed an exclusive, long-term distribution agreement with Terumo Corporation (Tokyo, Japan) for Sylys Surgical Sealant. Under the terms of the distribution agreement, Terumo Corporation (a leading provider of high quality, innovative medical devices), will have the exclusive rights to market Sylys in Japan.


Sylys Surgical Sealant

A Revolutionary Solution


  • Sylys Surgical Sealant is a resorbable synthetic sealant designed to help reduce anastomotic leakage in colectomy procedures by providing additional support to the anastomosis during the first few days of healing when the development of leaks is most likely to occur.
  • Sylys is intended to be used as an adjunct to standard closure techniques for the reinforcement and protection of anastomotic junctions.

Patrick Daly, President & CEO, Cohera Medical, says:

“Entering into a distribution arrangement with such a preeminent medical device manufacturer as Terumo validates the hard work completed on Sylys Surgical Sealant, the robust market, and the enormous potential of the technology. We are looking forward to working with Terumo to bring this important lifesaving technology to the Japanese market.”

Anastomotic leakage occurs in up to 23 percent of patients undergoing colorectal surgery and is considered to be the most serious surgical complication encountered, frequently resulting in the rapid development of severe peritonitis, septic shock, multiple organ dysfunction, and death{Alberts, 2003 #1}. At least one third of post-surgical deaths following colorectal surgery are attributed to leaks.

In Benefit of Patients


Keiko Kitamura, General Manager, Surgical Division, General Hospital Company, Terumo Corporation, says:

“The addition of Sylys Surgical Sealant is in perfect synergy with Terumo’s continued advancement into surgical products in Japan. We plan to work together with Cohera to move Sylys through the regulatory process in Japan as quickly as possible to the great benefit of our patients.”

The Distribution Agreement provides for license and marketing rights to the Sylys Surgical Sealant product for current and future indications in Japan. This represents a significant market opportunity for both companies as there are nearly a half million colorectal procedures each year collectively in the US and Japan. To date, no other products have been approved for the reduction of colorectal leaks and Sylys is well positioned to fill this unmet medical need.

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Source: Cohera
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