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Institute for Pediatric Innovation to Pursue Development of Adhesive System for Neonatals

Published on 2011-01-11. Author : SpecialChem

Cambridge, Mass. -- The Institute for Pediatric Innovation, working with Brigham and Women's Hospital and Children's Mercy Hospitals and Clinics, has been awarded a $340,000 grant from Philips Healthcare to pursue the development of an adhesive system tailored for use in neonatal intensive care units (NICUs).

Research has shown a need for developmentally friendly adhesives for premature babies, due to the fragile nature of their skin.

"Philips is committed to working with leading institutions in the development of developmentally friendly products and solutions for premature babies and their caregivers," said Bill Thompson, general manager of Philips Children's Medical Ventures, a provider of products and educational services that support developmental care for premature infants. "This project is important to Philips, because finding a solution to a fundamental problem affecting some of the most vulnerable patients has the potential to help improve and save lives."

The development efforts will be led by Dr. Jeffrey Karp, Co-director of the Center for Regenerative Therapeutics at Brigham and Women's Hospital. Dr. Karp leads a team of 30 researchers working at the interface of material science, biology, engineering and medicine, and he has highly relevant experience in working with advanced medical adhesive materials. In particular, one of his medical adhesive technologies was recognized in 2009 by Popular Mechanics as one of the "Top 20 New Biotech Breakthroughs that Will Change Medicine."

Dr. Karp reports that "neonatal patients represent an underserved population and our proposed solution will bring better care to the expanding population of premature infants." Children's Mercy Hospitals and Clinics, which operates in Missouri and Kansas, will lend clinical support to the development process by having two NICU clinical specialists advise the researchers as they develop this new medical device.

"This product will be very important in the field of neonatal care," stated Dr. Howard Kilbride, Chief of Neonatology at Children's Mercy Hospitals and Clinics, "It will have the potential for significant use in most NICUs and will help to significantly reduce an important clinical challenge that we now face."

IPI conducted a national needs assessment process in the IPI Pediatric Hospital Consortium that indicated specific unmet needs related to neonatal adhesive devices. "Based on IPI's survey work with our hospital consortium, we have determined that a priority need in NICUs is a gentle adhesive system that is tailored for the fragile skin of neonates," explained Don Lombardi, founder and CEO of IPI. "We are delighted to be working with Dr. Karp's world-class research team to address this need."

About The Institute for Pediatric Innovation

The Institute for Pediatric Innovation, a nonprofit 501(c)(3) organization, is improving pediatric care by stimulating development of medical devices and drugs designed specifically for treating babies and children. IPI and its consortium of seven leading U.S. pediatric hospitals work with the pediatric care community to identify and design the most needed products. IPI mobilizes public, private, nonprofit and for-profit resources to achieve product development and licenses the resulting products to companies for commercial sale. IPI is led by an experienced team of experts in licensing, developing and commercializing medical devices and pharmaceutical products for pediatric medical care. To date, IPI has aggregated financing from its consortium members, the Ewing Marion Kauffman Foundation, Philips Children's Medical Ventures, Inc., AGA Medical, Oxford Bioscience Partners, University of Kansas, Cambridge Consulting and the Food and Drug Administration (FDA).

About Brigham and Women's Hospital

Brigham and Women's Hospital (BWH) is a 793-bed nonprofit teaching affiliate of Harvard Medical School and a founding member of Partners HealthCare, an integrated health care delivery network. BWH is the home of the Carl J. and Ruth Shapiro Cardiovascular Center, the most advanced center of its kind. BWH is committed to excellence in patient care with expertise in virtually every specialty of medicine and surgery. The BWH medical preeminence dates back to 1832, and today that rich history in clinical care is coupled with its national leadership in quality improvement and patient safety initiatives and its dedication to educating and training the next generation of health care professionals. Through investigation and discovery conducted at its Biomedical Research Institute (BRI), BWH is an international leader in basic, clinical and translational research on human diseases, involving more than 900 physician-investigators and renowned biomedical scientists and faculty supported by more than $537 M in funding. BWH is also home to major landmark epidemiologic population studies, including the Nurses' and Physicians' Health Studies and the Women's Health Initiative.

About Children's Mercy Hospitals and Clinics

Children's Mercy Hospitals and Clinics, located in Kansas City, Mo., is one of the nation's top pediatric medical centers. The 317-bed hospital provides care for children from birth through the age of 18, and has been recognized by the American Nurses Credentialing Center with Magnet designation for excellence in nursing services, and ranked by U.S. News & World Report as one of "America's Best Children's Hospitals." Its faculty of 600 pediatricians and researchers across more than 40 subspecialties are actively involved in clinical care, pediatric research, and educating the next generation of pediatric subspecialists.

Source: Institute for Pediatric Innovation

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