Isocyanates are highly reactive chemicals which to a certain extent explains their effectiveness in various adhesive applications. Consequently, adhesive formulations containing isocyanates must have reasonable protection from contact with agents that combine with the isocyanate group including moisture. Reasonable caution must also be exerted in the use of materials containing isocyanate including adequate ventilation and prompt washing of body areas coming in contact.
This article describes recent developments in the area of non-isocyanate polyurethanes that are claimed to be safer and less toxic than conventional polyurethane adhesives and sealants.